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Cardiolipin CL is a diglycerol phospholipid mostly found in mitochondria where it optimizes numerous processes, including oxidative phosphorylation OXPHOS. To function properly, CL needs to be unsaturated, which requires the acyltransferase tafazzin. Interestingly, overexpression of Odc1p was also shown previously to rescue yeast models of mitochondrial diseases caused by defects in the assembly of ATP synthase and by mutations in the MPV17 protein that result in hepatocerebral mitochondrial DNA depletion syndrome.

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A year-old woman was pulled from the window of a burning building and found to be in cardiac arrest with pulseless electrical activity. Standard advanced cardiac life-support was started, and infusion of intra-osseous hydroxocobalamin OHCob was administered at the time of intubation because of the concern for cyanide CN gas exposure during smoke inhalation. Return of spontaneous circulation occurred before arrival at the hospital.

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Metrics details. The specificity of synaptic connections is fundamental for proper neural circuit function. Specific neuronal connections that underlie information processing in the sensory cortex are initially established without sensory experiences to a considerable extent, and then the connections are individually refined through sensory experiences.

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Acute pancreatitis is a sudden inflammation of the pancreas. Causes in order of frequency include a gallstone impacted in the common bile duct beyond the point where the pancreatic duct joins it; heavy alcohol use ; systemic disease ; trauma ; and, in minors, mumps. Acute pancreatitis may be a single event; it may be recurrent ; or it may progress to chronic pancreatitis.

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The Public Inspection page on FederalRegister. The Public Inspection page may also include documents scheduled for later issues, at the request of the issuing agency. The President of the United States manages the operations of the Executive branch of Government through Executive orders.

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Total quality in laboratory medicine should be defined as the guarantee that each activity throughout the total testing process is correctly performed, providing valuable medical decision-making and effective patient care. In the past decades, a fold reduction in the analytical error rate has been achieved thanks to improvements in both reliability and standardization of analytical techniques, reagents, and instrumentation. Notable advances in information technology, quality control and quality assurance methods have also assured a valuable contribution for reducing diagnostic errors.

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Due to these special conditions, the human microflora can undergo unusual changes and may represent health risks for the crew. The antimicrobial materials were exposed on the ISS for 6, 12, and 19 months each at a place frequently visited by the crew. On all three materials, surviving bacteria were dominated by Gram-positive bacteria and among those by Staphylococcus, Bacillus and Enterococcus spp. The novel antimicrobial surface coating proved to be highly effective.

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Heparinalso known as unfractionated heparin UFHis a medication and naturally occurring glycosaminoglycan. Common side effects include bleeding, pain at the injection site, and low blood platelets. The discovery of heparin was announced in Heparin acts as an anticoagulant, preventing the formation of clots and extension of existing clots within the blood.

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